Publicaciones científicas

En Oryzon realizamos investigación de vanguardia en los campos oncológico y neurodegenerativo.


Genómica / Bioinformática / Biomarcadores

1. Molecular diagnostics of endometrial cancer from uterine aspirate. Pérez-Sánchez C, Colas E, Cabrera S, Falcon O, Sanchez-del-Río A, García E, Fernández-de-Castillo L, Muruzabal JC, Alvarez E, Fiol G, González C, Torrejón R, Moral E, Campos M, Repollés M, Carreras R, Jiménez-López J, Xercavins J, Aibar E, Perdones-Montero A, Lalanne E, Palicio M,  Maes T, et al. Int J Cancer. 2013,133: 2383-2391.

2. Molecular markers of endometrial carcinoma detected in uterine aspirates. Colas E, Perez C, Cabrera S, Pedrola N, Monge M, Castellvi J, Eyzaguirre F, Gregorio J, Ruiz A, Llaurado M, Rigau M, Garcia M, Ertekin T, Montes M, Lopez-Lopez R, Carreras R, Xercavins J, Ortega A, Maes T, et al.. Int J Cancer. 2011,129:2435--2444.

3. Development of a novel splice array platform and its application in the identification of alternative splice variants in lung cancer.  Pio R, Blanco D, Pajares MJ, Aibar E, Durany O, Ezponda T, Agorreta J, Gomez-Roman J, Anton MA, Rubio A, Lozano MD, López-Picazo JM, Subirada F, Maes T, Montuenga LM. BMC Genomics. 3 de junio de 2010 3;11:352.

4. Orymold: ontology based gene expression data integration and analysis tool applied to rice.  Mercadé J, Espinosa A, Adsuara JE, Adrados R, Segura J, Maes T. BMC Bioinformatics. 23 de mayo de 2009:10:158.

5. Genomic resources for a commercial flatfish, the Senegalese sole (Solea senegalensis): EST sequencing, oligo microarray design, and development of the Soleamold bioinformatic platform. Cerdà J, Mercadé J, Lozano JJ, Manchado M, Tingaud-Sequeira A, Astola A, Infante C, Halm S, Viñas J, Castellana B, Asensio E, Cañavate P, Martínez-Rodríguez G, Piferrer F, Planas JV, Prat F, Yúfera M, Durany O, Subirada F, Rosell E, Maes T. BMC Genomics. 30 de octubre de 2008:9:508.

6. DNA Chip Technology in Brain Banks: Confronting a Degrading World. Buesa, Carlos  Maes, Tamara; Subirada, Francesc; Barrachina, Marta; Ferrer, Isidro Journal of Neuropathology & Experimental Neurology: Octubre de 2004 - Volumen 63 - Número 10 - págs. 1003-1014

Epigenética

1. KDM1 histone lysine demethylases as targets for treatments of oncological and neurodegenerative disease. Maes T, Mascaró C, Ortega A, Lunardi S, Ciceri F, P Somervaille TC, Buesa C.  Epigenomics, 2015 Jun;7(4):609-26. doi: 10.2217/epi.15.9 Review.

2. Advances in the development of histone lysine demethylase inhibitors. Maes T, Carceller E, Salas J, Ortega A, Buesa C.  Curr Opin Pharmacol. 5 de junio de 2015:23:52-60, doi: 10.1016/j.coph.2015.05.009. Review.  PMID: 26057211

3. Activity of highly selective LSD1 inhibitors in HCT-116 xenograft mice. T. Maes, J. Castro, A. Ortega and N. Guibourt Journal of Clinical Oncology, 2010 ASCO Annual Meeting Abstracts. Vol 28, Noº15_suppl (suplemento del 20 de mayo), 2010: e13663