Scientific Publications

At ORYZON we do cutting edge research in the oncological and neurodegenerative fields.


Genomics / Bioinformatics / Biomarkers

1. Molecular diagnostics of endometrial cancer from uterine aspirate. Pérez-Sánchez C, Colas E, Cabrera S, Falcon O, Sanchez-del-Río A, García E, Fernández-de-Castillo L, Muruzabal JC, Alvarez E, Fiol G, González C, Torrejón R, Moral E, Campos M, Repollés M, Carreras R, Jiménez-López J, Xercavins J, Aibar E, Perdones-Montero A, Lalanne E, Palicio M,  Maes T, et al.  Int J Cancer. 2013,133: 2383-2391.

2. Molecular markers of endometrial carcinoma detected in uterine aspirates. Colas E, Perez C, Cabrera S, Pedrola N, Monge M, Castellvi J, Eyzaguirre F, Gregorio J, Ruiz A, Llaurado M, Rigau M, Garcia M, Ertekin T, Montes M, Lopez-Lopez R, Carreras R, Xercavins J, Ortega A, Maes T, et al.. Int J Cancer. 2011,129:2435--2444.

3. Development of a novel splice array platform and its application in the identification of alternative splice variants in lung cancer.  Pio R, Blanco D, Pajares MJ, Aibar E, Durany O, Ezponda T, Agorreta J, Gomez-Roman J, Anton MA, Rubio A, Lozano MD, López-Picazo JM, Subirada F, Maes T, Montuenga LM. BMC Genomics. 2010 Jun 3;11:352.

4. Orymold: ontology based gene expression data integration and analysis tool applied to rice.  Mercadé J, Espinosa A, Adsuara JE, Adrados R, Segura J, Maes T. BMC Bioinformatics. 2009 May 23;10:158

5. Genomic resources for a commercial flatfish, the Senegalese sole (Solea senegalensis): EST sequencing, oligo microarray design, and development of the Soleamold bioinformatic platform. Cerdà J, Mercadé J, Lozano JJ, Manchado M, Tingaud-Sequeira A, Astola A, Infante C, Halm S, Viñas J, Castellana B, Asensio E, Cañavate P, Martínez-Rodríguez G, Piferrer F, Planas JV, Prat F, Yúfera M, Durany O, Subirada F, Rosell E, Maes T. BMC Genomics. 2008 Oct 30;9:508.

6. DNA Chip Technology in Brain Banks: Confronting a Degrading World. Buesa, Carlos  Maes, Tamara; Subirada, Francesc; Barrachina, Marta; Ferrer, Isidro Journal of Neuropathology & Experimental Neurology: October 2004 - Volume 63 - Issue 10 - p 1003–1014

Epigenetics

1. KDM1 histone lysine demethylases as targets for treatments of oncological and neurodegenerative disease Maes T, Mascaró C, Ortega A, Lunardi S, Ciceri F, P Somervaille TC, Buesa C.  Epigenomics, 2015 Jun;7(4):609-26. doi: 10.2217/epi.15.9 Review.

2. Advances in the development of histone lysine demethylase inhibitors. Maes T, Carceller E, Salas J, Ortega A, Buesa C.  Curr Opin Pharmacol. 2015 Jun 5;23:52-60. doi: 10.1016/j.coph.2015.05.009. Review.  PMID: 26057211

3. Activity of highly selective LSD1 inhibitors in HCT-116 xenograft mice. T. Maes, J. Castro, A. Ortega and N. Guibourt Journal of Clinical Oncology, 2010 ASCO Annual Meeting Abstracts. Vol 28, No 15_suppl (May 20 Supplement), 2010: e13663